Metabolic control over the oxygen consumption flux in intact skeletal muscle: in silico studies
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Metabolic control over the oxygen consumption flux in intact skeletal muscle: in silico studies.
It has been postulated previously that a direct activation of all oxidative phosphorylation complexes in parallel with the activation of ATP usage and substrate dehydrogenation (the so-called each-step activation) is the main mechanism responsible for adjusting the rate of ATP production by mitochondria to the current energy demand during rest-to-work transition in intact skeletal muscle in viv...
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Igo-192. rggg.---The surgical technique of isolation of the blood supply of the gracilis muscle of the dog has been developed for analysis of the oxygen consumption during reactive hyperemia. The time course of the blood flow, A-V oxygen difference and the oxygen consumption follow the same pattern. Immediately after the release of the arterial occlusion, there is an increase in all three value...
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WHALEN, W.J., D. BUERK, AND CLAIRE ANN THUNING. Blood jlow-limited oxygen consumption in resting cat skeletal muscle. Am. J. Physiol. 224(4) : 763-768. 1973.-In isolated, autoperfused preparations of the cat soleus (n = 10) and gracilis (n = 9) muscles, blood flow and venous and tissue Po2 were measured at several levels of perfusion pressure. Oxygen consumption (Vo2, steadystate conditions) de...
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DURAN, WALTER N., AND EUGENE M. RENKIN. Oxygen consumption and blood flow in resting mammalian skeletal mu&e. Am. J. Physiol. 226(l) : 173-l 77. 1974.-Of a total of 35 isolated blood-perfused, resting dog gracilis muscles, 25 maintained constant oxygen uptake (~oz) at all blood flows (Q) b a ove 2 ml/min X 100 g. In nine muscles, ~OZ varied with Q up to at least 10 ml/min x 100 g, reaching valu...
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BACKGROUND Organ dysfunction and tissue hypoxia in severe falciparum malaria result from an imbalance between oxygen delivery and demand. In severe malaria, microvascular obstruction from parasite sequestration decreases oxygen delivery. However, host microvascular function (defined as the capacity to increase oxygen delivery in response to ischemia) and oxygen consumption have not been assesse...
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ژورنال
عنوان ژورنال: AJP: Cell Physiology
سال: 2006
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00078.2006